Principal Scientist Oligonucleotide Translational Science (Billerica MA)

Work Your Magic with us! Start your next chapter and join EMD Serono.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 

Your Role:

• Define and execute translational strategies for oligonucleotide programs from discovery to preclinical stage
• Develop in house qPCR, Nan string, Western and fluorescent readouts to quantify mRNA knockdown, splice modulation, and protein KD.
• Integrate in vitro potency, off target, innate immune to drive SAR with Oligo Chemist and Bioinformatics.
• Design and interpret efficacy, and safety relationships for siRNA, ASO and AOC modalities and utilize translational approaches
• Develop translational screening cascade to prioritize oligo constructs, Conjugates and delivery strategies
• Strategic thinking with strong scientific rigor and ability to work at the interface of discovery and clinical development.
• Track progress against project timelines, generate regular status updates, and communicate progress and issues to management

Who You Are

Minimum Qualifications:

• PhD in Molecular Biology, Pharmacology, Immunology or related disciplines with minimum 5 years of related industry experience.

Preferred Qualifications:

• Proven track working with Oligonucleotide modalities like ASO’s and siRNAs
• Experience with LCMS-based analytical method development desired.
• Knowledge of GxP requirements and application of statistical methods in the analytical laboratory is a plus.
• Strong interpersonal skills, communication, and collaboration.

Location:  Billerica MA

Pay Range for this position: $192,000 - $193,400

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Job Requisition ID:  299092

Location:  Billerica

Career Level:  D - Professional (4-9 years)

Working time model:  Full-time

North America Disclosure
The Company is committed to accessibility in its workplaces, including during the job application process. Applicants who may require accommodation during the application process should speak with our Candidate Services team at 844-655-6466 from 8:00am to 5:30pm ET Monday through Friday. If you are a resident of a Connecticut or Colorado, you are eligible to receive additional information about the compensation and benefits, which we will provide upon request.  You may contact 855 444 5678 from 8:00am to 5:30pm ET Monday through Friday, for assistance.

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Job Segment: R&D, Research Scientist, Molecular Biology, Biology, Chemistry, Research, Science

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